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aspen plus® version 8.6 chemical process simulation software  (Aspen Technology Inc)
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fdtdsolution software  (Lumerical Solutions)
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superpro designer version 8.5  (Intelligen Inc)
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gastroplus software (version 8.5)  (Simulations Plus Inc)
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Gastroplus Software (Version 8.5), supplied by Simulations Plus Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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imagequant software version 8.1  (Molecular Dynamics Inc)
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pbpk model commercial software gastroplus  (Simulations Plus Inc)
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<t> PBPK </t> model of lacidipine based on the literature data.
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wind turbine simulator fast version 8  (MathWorks Inc)
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<t> PBPK </t> model of lacidipine based on the literature data.
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easyspin 5.1.0 simulation toolkit functions for  (MathWorks Inc)
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<t> PBPK </t> model of lacidipine based on the literature data.
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population-based adme simulator version 8.2 sp2  (Simcyp)
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<t> PBPK </t> model of lacidipine based on the literature data.
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gastroplus pbpk model  (Simulations Plus Inc)
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Simulations Plus Inc gastroplus pbpk model
Input data used in the <t> GastroPlus </t> PBPK model.
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Image Search Results


PBPK model of lacidipine based on the literature data.

Journal: Asian Journal of Pharmaceutical Sciences

Article Title: Virtual population pharmacokinetic using physiologically based pharmacokinetic model for evaluating bioequivalence of oral lacidipine formulations in dogs

doi: 10.1016/j.ajps.2016.03.003

Figure Lengend Snippet: PBPK model of lacidipine based on the literature data.

Article Snippet: In this study, all the in vivo PK simulations were conducted in the PBPK model commercial software GastroPlus (Version 8.6.0003; Simulations Plus, Inc., Lancaster, CA, USA).

Techniques: Permeability, Diffusion-based Assay, Solubility, Clinical Proteomics

Input data used in the GastroPlus PBPK model.

Journal: Acta Pharmacologica Sinica

Article Title: Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model

doi: 10.1038/aps.2015.118

Figure Lengend Snippet: Input data used in the GastroPlus PBPK model.

Article Snippet: The GastroPlus (version 8.6; Simulations Plus, Inc, Lancaster, CA, USA) PBPK model was used for all intravenous and oral simulations in preclinical species and humans.

Techniques: Molecular Weight, Permeability, Solubility, Clinical Proteomics

Observed and PBPK-model-predicted plasma-concentration-versus-time profiles of TPN729MA after intravenous administration to rats (A) or dogs (B) and oral administration to rats (C) or dogs (D). Open circles represent observed data from individual animals, and solid lines represent the profiles predicted from the PBPK model in GastroPlus. Doses were 1 mg/kg (iv) and 10 mg/kg (po) in rats and 3 mg/kg (iv) and 3 mg/kg (po) in dogs.

Journal: Acta Pharmacologica Sinica

Article Title: Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model

doi: 10.1038/aps.2015.118

Figure Lengend Snippet: Observed and PBPK-model-predicted plasma-concentration-versus-time profiles of TPN729MA after intravenous administration to rats (A) or dogs (B) and oral administration to rats (C) or dogs (D). Open circles represent observed data from individual animals, and solid lines represent the profiles predicted from the PBPK model in GastroPlus. Doses were 1 mg/kg (iv) and 10 mg/kg (po) in rats and 3 mg/kg (iv) and 3 mg/kg (po) in dogs.

Article Snippet: The GastroPlus (version 8.6; Simulations Plus, Inc, Lancaster, CA, USA) PBPK model was used for all intravenous and oral simulations in preclinical species and humans.

Techniques: Clinical Proteomics, Concentration Assay